OPK · Nasdaq · CIK 0000944809

OPKO HEALTH, INC.

OPKO HEALTH, INC.’s most recent SEC filing in our snapshot is a Form 8-K filed on Oct 15, 2026. In fiscal 2025 (year ended Dec 31, 2025) it reported revenue of $606.9M and net income of -$225.7M, according to its XBRL data on EDGAR. Its EDGAR record lists 15 Form 4 insider filings from the 12 months before our last refresh.

SEC EDGAR snapshot updated Oct 27, 2026, 11:27 PM EDT. See all filings on sec.gov.

Revenue, FY2025
$606.9M
Net income, FY2025
-$225.7M
Form 4 filings on record, past 12 months
15

Company overview

Legal name (as filed)
OPKO HEALTH, INC.
Ticker
OPK
SEC Central Index Key (CIK)
0000944809
Industry (SIC)
Pharmaceutical Preparations (code 2834)
Business address
MIAMI, FL
State or country of incorporation
DE
Fiscal year ends
December 31
SEC filer category
Accelerated filer
Position in SEC ticker list
#2294 of the 3,000 companies we track

Five-year financial highlights

Full-year figures from OPKO HEALTH, INC.’s annual reports, as tagged in XBRL and published by the SEC. Amounts are in U.S. dollars; the fiscal year is named for the calendar year in which it ends.

Revenue
$1.8BFY2021$1.0BFY2022$863.5MFY2023$713.1MFY2024$606.9MFY2025
Net income
-$30.1MFY2021-$328.4MFY2022-$188.9MFY2023-$53.2MFY2024-$225.7MFY2025
OPK annual results
ItemFY2021
ended Dec 31, 2021		FY2022
ended Dec 31, 2022		FY2023
ended Dec 31, 2023		FY2024
ended Dec 31, 2024		FY2025
ended Dec 31, 2025
Revenue$1.8B$1.0B$863.5M$713.1M$606.9M
Net income-$30.1M-$328.4M-$188.9M-$53.2M-$225.7M
Diluted EPS-$0.05-$0.46-$0.25-$0.08-$0.30
Total assets$2.4B$2.2B$2.0B$2.2B$1.9B
Cash and equivalents$134.7M$153.2M$95.9M$426.6M$364.4M

XBRL tags used: revenue = RevenueFromContractWithCustomerExcludingAssessedTax; netIncome = NetIncomeLoss; assets = Assets; eps = EarningsPerShareDiluted; cash = CashAndCashEquivalentsAtCarryingValue. EPS is shown as originally reported for each year and may not be adjusted for later stock splits. A dash means the company did not report that item in a form we could match.

How to read these numbers

Revenue is the money a company brings in from selling its products and services; net income is what is left after all expenses, interest and taxes. Diluted EPS spreads net income across every share that could exist if options and convertible securities were exercised. Total assets and cash are balance-sheet figures measured on the last day of the fiscal year. For the full story — segment results, one-time charges, guidance — read Management’s Discussion and Analysis in the Form 10-K.

Latest key reports

The most recent filing of each major report type, even if it falls outside the 40 newest filings below.

OPK latest annual, quarterly, current and proxy reports
FiledFormWhat it isOriginal
Feb 26, 202610-KAnnual report· period Dec 31, 2025Document · Index
Jul 27, 202610-QQuarterly report· period Jun 30, 2026Document · Index
Oct 15, 20268-KMaterial agreement· period Oct 14, 2026Document · Index
Apr 30, 2026DEF 14ADefinitive proxy statement· period Apr 30, 2026Document · Index

Recent SEC filings

The 40 newest documents filed by or about OPKO HEALTH, INC., by form type:

4 ×168-K ×1010-Q ×310-Q/A ×2SCHEDULE 13D/A ×2DEFA14A ×23 ×1SCHEDULE 13D ×1ARS ×1DEF 14A ×110-K ×1
OPK recent filings
FiledFormWhat it isOriginal
Oct 15, 20268-KMaterial agreement· period Oct 14, 2026Document · Index
Oct 2, 20268-KOther events· period Sep 30, 2026Document · Index
Aug 28, 202610-Q/AQuarterly report· period Jun 30, 2026Document · Index
Aug 28, 202610-Q/AQuarterly report· period Mar 31, 2026Document · Index
Aug 14, 20268-KMaterial agreement; New financial obligation· period Aug 13, 2026Document · Index
Aug 7, 2026SCHEDULE 13DActive beneficial ownership report (over 5%)Document · Index
Jul 28, 20264Statement of changes in beneficial ownership (insider trade)· period Jul 24, 2026Document · Index
Jul 28, 20264Statement of changes in beneficial ownership (insider trade)· period Jul 24, 2026Document · Index
Jul 27, 202610-QQuarterly report· period Jun 30, 2026Document · Index
Jul 27, 20268-KResults of operations· period Jul 27, 2026Document · Index
Jul 1, 2026SCHEDULE 13D/AActive beneficial ownership report (over 5%)Document · Index
Jun 22, 20264Statement of changes in beneficial ownership (insider trade)· period Jun 18, 2026Document · Index
Jun 22, 20264Statement of changes in beneficial ownership (insider trade)· period Jun 18, 2026Document · Index
Jun 22, 20264Statement of changes in beneficial ownership (insider trade)· period Jun 18, 2026Document · Index
Jun 22, 20264Statement of changes in beneficial ownership (insider trade)· period Jun 18, 2026Document · Index
Jun 22, 20264Statement of changes in beneficial ownership (insider trade)· period Jun 18, 2026Document · Index
Jun 22, 20264Statement of changes in beneficial ownership (insider trade)· period Jun 18, 2026Document · Index
Jun 18, 20268-KShareholder vote results· period Jun 18, 2026Document · Index
May 15, 2026DEFA14AAdditional proxy soliciting materialsDocument · Index
Apr 30, 2026ARSARS· period Dec 31, 2025Document · Index
Apr 30, 2026DEFA14AAdditional proxy soliciting materialsDocument · Index
Apr 30, 2026DEF 14ADefinitive proxy statement· period Apr 30, 2026Document · Index
Apr 28, 202610-QQuarterly report· period Mar 31, 2026Document · Index
Apr 28, 20268-KResults of operations· period Apr 28, 2026Document · Index
Mar 20, 20264Statement of changes in beneficial ownership (insider trade)· period Mar 20, 2026Document · Index
Mar 20, 20264Statement of changes in beneficial ownership (insider trade)· period Mar 18, 2026Document · Index
Mar 20, 20263Initial statement of beneficial ownership· period Mar 18, 2026Document · Index
Mar 19, 20268-KDirector or officer change· period Mar 18, 2026Document · Index
Feb 26, 202610-KAnnual report· period Dec 31, 2025Document · Index
Feb 26, 20268-KResults of operations· period Feb 26, 2026Document · Index
Nov 21, 20254Statement of changes in beneficial ownership (insider trade)· period Nov 21, 2025Document · Index
Nov 20, 20254Statement of changes in beneficial ownership (insider trade)· period Nov 20, 2025Document · Index
Nov 19, 20254Statement of changes in beneficial ownership (insider trade)· period Nov 19, 2025Document · Index
Nov 18, 20254Statement of changes in beneficial ownership (insider trade)· period Nov 18, 2025Document · Index
Oct 31, 20254Statement of changes in beneficial ownership (insider trade)· period Oct 31, 2025Document · Index
Oct 29, 202510-QQuarterly report· period Sep 30, 2025Document · Index
Oct 29, 20258-KResults of operations· period Oct 29, 2025Document · Index
Oct 1, 2025SCHEDULE 13D/AActive beneficial ownership report (over 5%)Document · Index
Sep 15, 20258-KRegulation FD disclosure; Other events· period Sep 15, 2025Document · Index
Aug 19, 20254Statement of changes in beneficial ownership (insider trade)· period Aug 18, 2025Document · Index

Insider filing activity

15 Form 4 filings appear in OPKO HEALTH, INC.’s EDGAR record between Oct 28, 2025 and our last refresh. Most are reports by the company’s own directors, officers and 10% owners, but EDGAR also lists a Form 4 under a company when the company itself is the insider — for example, when it owns more than 10% of another public company. Foreign private issuers’ own insiders generally do not file Form 4. A high count is not by itself a signal: many Form 4s report routine stock awards, tax withholding or sales under pre-arranged Rule 10b5-1 plans. Open each filing to see the transaction code, share count and price. What a Form 4 shows.

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Source

  • U.S. Securities and Exchange Commission, EDGAR submissions for CIK 0000944809 and XBRL company facts. OPKO HEALTH, INC. on EDGAR.
  • Snapshot updated Oct 27, 2026, 11:27 PM EDT. The SEC does not endorse OpenFilings. Company names and tickers are used only to identify the filer; no logos are shown.

Not investment advice. This page summarizes public SEC filings for information only. Figures may contain errors or omissions; confirm everything in the original filing before relying on it.