KRYS · Nasdaq · CIK 0001711279

Krystal Biotech, Inc.

Krystal Biotech, Inc.’s most recent SEC filing in our snapshot is a Form SCHEDULE 13G/A filed on Oct 27, 2026. In fiscal 2025 (year ended Dec 31, 2025) it reported revenue of $389.1M and net income of $204.8M, according to its XBRL data on EDGAR. Its EDGAR record lists 24 Form 4 insider filings from the 12 months before our last refresh.

SEC EDGAR snapshot updated Oct 27, 2026, 11:27 PM EDT. See all filings on sec.gov.

Revenue, FY2025
$389.1M
Net income, FY2025
$204.8M
Form 4 filings on record, past 12 months
24

Company overview

Legal name (as filed)
Krystal Biotech, Inc.
Ticker
KRYS
SEC Central Index Key (CIK)
0001711279
Business address
PITTSBURGH, PA
State or country of incorporation
—
Fiscal year ends
December 31
SEC filer category
Large accelerated filer
Position in SEC ticker list
#940 of the 3,000 companies we track

Five-year financial highlights

Full-year figures from Krystal Biotech, Inc.’s annual reports, as tagged in XBRL and published by the SEC. Amounts are in U.S. dollars; the fiscal year is named for the calendar year in which it ends.

Revenue
$0FY2021$0FY2022$50.7MFY2023$290.5MFY2024$389.1MFY2025
Net income
-$69.6MFY2021-$140.0MFY2022$10.9MFY2023$89.2MFY2024$204.8MFY2025
KRYS annual results
ItemFY2021
ended Dec 31, 2021		FY2022
ended Dec 31, 2022		FY2023
ended Dec 31, 2023		FY2024
ended Dec 31, 2024		FY2025
ended Dec 31, 2025
Revenue$0$0$50.7M$290.5M$389.1M
Net income-$69.6M-$140.0M$10.9M$89.2M$204.8M
Diluted EPS-$3.13-$5.49$0.39$3.00$6.84
Total assets$626.3M$558.5M$818.4M$1.1B$1.3B
Cash and equivalents$341.2M$161.9M$358.3M$344.9M$496.3M

XBRL tags used: revenue = RevenueFromContractWithCustomerExcludingAssessedTax; netIncome = NetIncomeLoss; assets = Assets; eps = EarningsPerShareDiluted; cash = CashAndCashEquivalentsAtCarryingValue. EPS is shown as originally reported for each year and may not be adjusted for later stock splits. A dash means the company did not report that item in a form we could match.

How to read these numbers

Revenue is the money a company brings in from selling its products and services; net income is what is left after all expenses, interest and taxes. Diluted EPS spreads net income across every share that could exist if options and convertible securities were exercised. Total assets and cash are balance-sheet figures measured on the last day of the fiscal year. For the full story — segment results, one-time charges, guidance — read Management’s Discussion and Analysis in the Form 10-K.

Latest key reports

The most recent filing of each major report type, even if it falls outside the 40 newest filings below.

KRYS latest annual, quarterly, current and proxy reports
FiledFormWhat it isOriginal
Feb 17, 202610-KAnnual report· period Dec 31, 2025Document · Index
Aug 3, 202610-QQuarterly report· period Jun 30, 2026Document · Index
Oct 15, 20268-KRegulation FD disclosure· period Oct 15, 2026Document · Index
Apr 3, 2026DEF 14ADefinitive proxy statement· period Apr 3, 2026Document · Index

Recent SEC filings

The 40 newest documents filed by or about Krystal Biotech, Inc., by form type:

4 ×15144 ×98-K ×5SCHEDULE 13G/A ×33 ×210-Q ×2SCHEDULE 13G ×1ARS ×1DEFA14A ×1DEF 14A ×1
KRYS recent filings
FiledFormWhat it isOriginal
Oct 27, 2026SCHEDULE 13G/APassive beneficial ownership report (over 5%)Document · Index
Oct 15, 20268-KRegulation FD disclosure· period Oct 15, 2026Document · Index
Sep 16, 20264Statement of changes in beneficial ownership (insider trade)· period Sep 14, 2026Document · Index
Sep 16, 20264Statement of changes in beneficial ownership (insider trade)· period Sep 14, 2026Document · Index
Sep 16, 20264Statement of changes in beneficial ownership (insider trade)· period Sep 14, 2026Document · Index
Sep 16, 20264Statement of changes in beneficial ownership (insider trade)· period Sep 14, 2026Document · Index
Sep 16, 20264Statement of changes in beneficial ownership (insider trade)· period Sep 14, 2026Document · Index
Sep 16, 20264Statement of changes in beneficial ownership (insider trade)· period Sep 14, 2026Document · Index
Sep 4, 2026144Notice of proposed sale of securitiesDocument · Index
Sep 4, 2026144Notice of proposed sale of securitiesDocument · Index
Sep 4, 20264Statement of changes in beneficial ownership (insider trade)· period Sep 4, 2026Document · Index
Sep 4, 20264Statement of changes in beneficial ownership (insider trade)· period Sep 4, 2026Document · Index
Aug 14, 2026144Notice of proposed sale of securitiesDocument · Index
Aug 14, 20264Statement of changes in beneficial ownership (insider trade)· period Aug 14, 2026Document · Index
Aug 3, 20268-KResults of operations· period Aug 3, 2026Document · Index
Aug 3, 202610-QQuarterly report· period Jun 30, 2026Document · Index
Jul 21, 20268-KOther events· period Jul 21, 2026Document · Index
Jun 26, 20264Statement of changes in beneficial ownership (insider trade)· period Jun 25, 2026Document · Index
Jun 25, 2026144Notice of proposed sale of securitiesDocument · Index
Jun 5, 20264Statement of changes in beneficial ownership (insider trade)· period Jun 4, 2026Document · Index
Jun 5, 20264Statement of changes in beneficial ownership (insider trade)· period Jun 4, 2026Document · Index
Jun 4, 2026144Notice of proposed sale of securitiesDocument · Index
Jun 4, 2026144Notice of proposed sale of securitiesDocument · Index
May 27, 20264Statement of changes in beneficial ownership (insider trade)· period May 26, 2026Document · Index
May 26, 2026144Notice of proposed sale of securitiesDocument · Index
May 20, 20268-KShareholder vote results· period May 15, 2026Document · Index
May 4, 20268-KCurrent report· period May 4, 2026Document · Index
May 4, 202610-QQuarterly report· period Mar 31, 2026Document · Index
May 4, 2026SCHEDULE 13G/APassive beneficial ownership report (over 5%)Document · Index
Apr 29, 2026SCHEDULE 13GPassive beneficial ownership report (over 5%)Document · Index
Apr 3, 2026ARSARS· period Dec 31, 2025Document · Index
Apr 3, 2026DEFA14AAdditional proxy soliciting materialsDocument · Index
Apr 3, 2026DEF 14ADefinitive proxy statement· period Apr 3, 2026Document · Index
Mar 27, 2026SCHEDULE 13G/APassive beneficial ownership report (over 5%)Document · Index
Mar 6, 20263Initial statement of beneficial ownership· period Mar 1, 2026Document · Index
Mar 6, 20263Initial statement of beneficial ownership· period Mar 1, 2026Document · Index
Mar 6, 20264Statement of changes in beneficial ownership (insider trade)· period Mar 4, 2026Document · Index
Mar 6, 20264Statement of changes in beneficial ownership (insider trade)· period Mar 4, 2026Document · Index
Mar 4, 2026144Notice of proposed sale of securitiesDocument · Index
Mar 4, 2026144Notice of proposed sale of securitiesDocument · Index

Insider filing activity

24 Form 4 filings appear in Krystal Biotech, Inc.’s EDGAR record between Oct 28, 2025 and our last refresh. Most are reports by the company’s own directors, officers and 10% owners, but EDGAR also lists a Form 4 under a company when the company itself is the insider — for example, when it owns more than 10% of another public company. Foreign private issuers’ own insiders generally do not file Form 4. A high count is not by itself a signal: many Form 4s report routine stock awards, tax withholding or sales under pre-arranged Rule 10b5-1 plans. Open each filing to see the transaction code, share count and price. What a Form 4 shows.

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Source

  • U.S. Securities and Exchange Commission, EDGAR submissions for CIK 0001711279 and XBRL company facts. Krystal Biotech, Inc. on EDGAR.
  • Snapshot updated Oct 27, 2026, 11:27 PM EDT. The SEC does not endorse OpenFilings. Company names and tickers are used only to identify the filer; no logos are shown.

Not investment advice. This page summarizes public SEC filings for information only. Figures may contain errors or omissions; confirm everything in the original filing before relying on it.